張旭志，男，博士，中國(guó)水產(chǎn)科學(xué)研究院黃海水產(chǎn)研究所研究員。中國(guó)水產(chǎn)科學(xué)研究院“百名科技英才”培育計(jì)劃第一批人選；中國(guó)海洋大學(xué)、上海海洋大學(xué)、大連海洋大學(xué)和青島科技大學(xué)研究生導(dǎo)師；澳大利亞新南威爾士大學(xué)公派訪問學(xué)者；中澳青年科學(xué)家交流計(jì)劃項(xiàng)目成員。從事生化傳感器及其應(yīng)用技術(shù)研究，國(guó)際首創(chuàng)高效電容耦合非接觸電導(dǎo)傳感概念，解決了流體、半流體介質(zhì)電導(dǎo)率值的準(zhǔn)確測(cè)定難題，突破了高通量在線監(jiān)測(cè)污水、血液等復(fù)雜樣品導(dǎo)電能力變化的技術(shù)瓶頸，開發(fā)出了多功能電子滴定儀、電子微生物生長(zhǎng)分析儀等自動(dòng)化裝備并構(gòu)建出化學(xué)滴定、藥敏試驗(yàn)、微生物快檢等系列應(yīng)用技術(shù)。主持完成國(guó)家級(jí)項(xiàng)目/課題3項(xiàng)、省部級(jí)項(xiàng)目/課題7項(xiàng)、其它縱向科研項(xiàng)目4項(xiàng)和橫向開發(fā)項(xiàng)目5項(xiàng)。第一作者/通訊作者發(fā)表SCI收錄論文40余篇，其中JCR一區(qū)15篇；獲授權(quán)中國(guó)發(fā)明專利8件（已轉(zhuǎn)讓4件）和美國(guó)發(fā)明專利1件。根據(jù)國(guó)家標(biāo)準(zhǔn)，第三方科研成果標(biāo)準(zhǔn)化評(píng)價(jià)機(jī)構(gòu)給與所完成科技成果“電子微生物生長(zhǎng)傳感器”和“八通道電子滴定儀”的評(píng)價(jià)結(jié)論皆為“整體水平達(dá)到國(guó)際領(lǐng)先”。獲省部級(jí)以上獎(jiǎng)勵(lì)、榮譽(yù)6項(xiàng)。成果“電子微生物生長(zhǎng)傳感器”獲第二十二屆中國(guó)國(guó)際高新技術(shù)成果交易會(huì)優(yōu)秀產(chǎn)品獎(jiǎng)。
主要研究方向：
1. 化學(xué)和生物傳感器
2. 微生物檢測(cè)技術(shù)
3. 漁業(yè)生態(tài)環(huán)境
代表性論文：
1. Xuzhi Zhang, Kui Jiao, Shufeng Liu, Yuwei Hu. A readily reusable electrochemical DNA hybridization biosensor based on the interaction of DNA with single-walled carbon nanotubes. Analytical Chemistry, 2009, 81, 6006-6012.
2. Xuzhi Zhang*, Wenwen Liu, Xun Lu, J. Justin Gooding, Qiufen Li, Keming Qu. Monitoring the progression of loop-mediated isothermal amplification (LAMP) using conductivity. Analytical Biochemistry, 2014, 466, 16-18.
3. Xuzhi Zhang, Xiaoyu Jiang, Qianqian Yang, Xiaochun Wang, Yan Zhang, Jun Zhao, Keming Qu*, Chuan Zhao*, Online monitoring of bacterial growth with electrical sensor, Analytical Chemistry, 2018, 90 (10), 6006-6011.
4. Xuzhi Zhang, Xiaoyu Jiang, Zhihui Hao, Keming Qu. Advances in online methods for monitoring microbial growth. Biosensors and Bioelectronics, 2019, 126, 433-447
5. Xuzhi Zhang, Xiaochun Wang, Qianqian Yang, Xiaoyu Jiang, Yang Li, Jun Zhao, Keming Qu*. Conductometric sensor for viable Escherichia coli and Staphylococcus aureus based on magnetic analyte separation via aptamer. Microchimica Acta, 2020, 187, 43.
6. Xuzhi Zhang, Xiaochun Wang, Hongrui Cheng, Yuanhui Zheng*, Jun Zhao, Keming Qu*. A universal automated method for determining the bacteriostatic activity of nanomaterials. Journal of Hazardous Materials, 2021, 413, 125320.
7. Xuzhi Zhang, Xiangyi Hou, Liangyu Ma, Yaqi Shi, Dahai Zhang*, Keming Qu*. Analytical methods for assessing antimicrobial activity of nanomaterials in complex media: Advances, challenges, and perspectives. Journal of Nanobiotechnology, 2023, 21, 97.
8. Xuzhi Zhang, Qianqian Yang, Liangyu Ma, Dahai Zhang*, Wentao Lin, Nick Schlensky, Hongrui Cheng, Yuanhui Zheng*, Xiliang Luo, Caifeng Ding, Yan Zhang, Xiangyi Hou, Feng Lu, Hua Yan, Ruoju Wang, Chen-Zhong Li*, Keming Qu*. Automatically showing growth kinetics with a high-performance microbial growth analyzer. Biosensors and Bioelectronics, 2023, 239, 115626.
9. Yuanyuan Zhang, Qianqian Yang, Feng Lu, Xiaoyang Wang, Ruohan Liang, Xiaodan Pu, Jianlei Chen, Dahai Zhang*, Zhixiang Chen, Xuzhi Zhang*. Inhibitory effects of potassium sorbate and ZnO nanoparticles on Escherichia coli and Staphylococcus aureus in milk-basedbeverage. International Dairy Journal, 2024, 159, 106073.
10. Jie Zheng, Xiaoyu Wang, Hongqing Qin, Yaxiao Hou, Qianqian Yang, Xuzhi Zhang*, Xu Hun*. Target-Navigated CBT–Cys “Stapling” Coupled with CRISPR/Cas12a Amplification for the Photoelectrochemical Nucleic Acid Assay.Analytical Chemistry, 2024, 96, 45, 18011-18019.
11. Xiaoyang Wang, Ruohan Liang, Xiaodan Pu, Yuanyuan Zhang, Feng Lu, Qianqian Yang, Xueting Zhu, Qing Kong*, Xuzhi Zhang*. Application of the Electrical Microbial Growth Analyzer Method for Efficiently Quantifying Viable Bacteria in Ready-to-Eat Sea Cucumber Products. Microorganisms, 2024, 12, 2301.
代表性發(fā)明專利：
1. 中國(guó)專利：非接觸式基因擴(kuò)增電化學(xué)快速檢測(cè)方法
2. 中國(guó)專利：一種鹽酸環(huán)丙沙星含量的檢測(cè)方法
3. 中國(guó)專利：一種自動(dòng)記錄大腸桿菌生長(zhǎng)曲線的裝置及應(yīng)用方法
4. 中國(guó)專利：一種革蘭氏陰性菌自動(dòng)藥敏試驗(yàn)裝置及應(yīng)用方法
5. 中國(guó)專利：電子微生物生長(zhǎng)傳感器檢測(cè)配套裝置
6. 美國(guó)專利：Device and Method for Automated Antibiotic Susceptibility Testing of Gram-Negative Bacteria
7. 中國(guó)專利：對(duì)蝦體內(nèi)可培養(yǎng)細(xì)菌總數(shù)檢測(cè)功能液、系統(tǒng)及方法
8. 中國(guó)專利：一種水體中副溶血弧菌的現(xiàn)場(chǎng)檢測(cè)試劑盒和檢測(cè)方法
制定標(biāo)準(zhǔn)：
1. 團(tuán)體標(biāo)準(zhǔn)（T/QDAS 122-2023）水質(zhì) 耐熱大腸菌群的測(cè)定 高效微生物生長(zhǎng)分析儀法
代表性儀器裝備研發(fā)成果：
1. 八通道電子滴定儀
2. 高通量電子微生物生長(zhǎng)傳感器
3. 高效微生物生長(zhǎng)分析儀
