碩士生導(dǎo)師

徐甲坤，男，1984年1月生人，于2011年9月獲日本名古屋大學(xué)生物無機(jī)化學(xué)專業(yè)博士學(xué)位，現(xiàn)任中國水產(chǎn)科學(xué)研究院黃海水產(chǎn)研究所科研處副處長，研究員，研究生導(dǎo)師。主要從事生物催化與轉(zhuǎn)化等方面的研究，主持國家自然科學(xué)基金（面上、青年）、科技部“高端外國專家引進(jìn)計(jì)劃”項(xiàng)目、農(nóng)業(yè)農(nóng)村部農(nóng)業(yè)國際交流合作項(xiàng)目、山東省重點(diǎn)研發(fā)計(jì)劃等10余項(xiàng)項(xiàng)目；在ACS Catalysis、Journal of Hazardous Materials、Biosensors and Bioelectronics、International Journal of Biological Macromolecules、Catalysis Science&Technology、Chemistry–A European Journal等國際知名期刊發(fā)表論文60余篇，其中第一/通訊作者SCI 40余篇；獲授權(quán)國家發(fā)明專利10余項(xiàng)（第一發(fā)明人6項(xiàng)）；主編副主編出版著作3部；入選中國水產(chǎn)科學(xué)研究院“百名英才培育計(jì)劃”、中國水產(chǎn)科學(xué)研究院“青年英才”拔尖人才，榮獲山東省海洋與漁業(yè)科學(xué)技術(shù)獎(jiǎng)青年科技獎(jiǎng)、中國水產(chǎn)科學(xué)研究院黃海水產(chǎn)研究所青年科技獎(jiǎng)；擔(dān)任中國水產(chǎn)科學(xué)研究院海洋生物酶工程創(chuàng)新團(tuán)隊(duì)副首席；兼任亞太水產(chǎn)養(yǎng)殖中心網(wǎng)（NACA）技術(shù)指導(dǎo)委員會(huì)委員、中國水產(chǎn)學(xué)會(huì)海水養(yǎng)殖分會(huì)秘書長、中國海洋大學(xué)校友高級(jí)專家協(xié)會(huì)副秘書長，山東大學(xué)、中國海洋大學(xué)、上海海洋大學(xué)、青島科技大學(xué)等高校研究生導(dǎo)師。

聯(lián)系電話：13869828530，0532-85812670

通訊地址：山東省青島市市南區(qū)南京路106號(hào)

郵政編碼：266071

E-mail：xujk@ysfri.ac.cn

代表性論著：

1. Ridong Yang, Osami Shoji, Yingwu Lin, Fang Wang, Hongxia Che, Jiakun Xu^*, Construction of P450 scaffold biocatalysts for the biodegradation of five chloroanilines， Journal of Hazardous Materials, 2025, 488, 137305.

2.Yadan Yang, Weikang Zhang, Fang Wang, Dong Li, Xiangmin Meng, Xiaochun Sun, Jiakun Xu*, Construction of biocatalysts based on P450BM3 for the degradation of non-steroidal anti-inflammatory drugs, Journal of Hazardous Materials, 2024, 480, 136097.

3. Weikang Zhang, Yingwu Lin, Xiangmin Meng, Qiaoning Wang, Lingxin Chen*, Jiakun Xu^*, Construction of a myoglobin scaffold-based biocatalyst for the biodegradation of sulfadiazine and sulfathiazole, Journal of Hazardous Materials, 2024, 465, 113147.

4. Sijia Zhao, Yingwu Lin, Jinghan Wang, Dong Li, Fang Wang, Osami Shoji, Jiakun Xu^*, Regioselective aromatic O-demethylation with an artificial P450BM3/sugar alcohol oxidase peroxygenase system, International Journal of Biological Macromolecules, 2025, 309, 142768.

5. Weikang Zhang, Yadan Yang, Xiangmin Meng,*, Fang Wang, Yingwu Lin*, Jiakun Xu^*, Construction of artificial peroxidase based on myoglobin scaffold for efficient degradation of meloxicam, Journal of Inorganic Biochemistry, 2025, 262, 112733.

6. Guangrong Wu, Jiakun Xu^*, Lijuan Sun, Yingfu Li, Shuqin Gao, Yingwu Lin^*, Application of engineered heme enzymes based on myoglobin with high peroxidase activity for efficient degradation of various emerging pollutants, Journal of Environmental Chemical Engineering, 2023, 11, 111471.

7. Bin Qiao^*, Jiakun Xu^*, Wenhao Yin, Wanmeng Xin, Lixin Ma, Jie Qiao^*, Yi Liu^*, “Aptamer-locker” DNA coupling with CRISPR/Cas12a-guided biosensing for high-efficiency melamine analysis, Biosensors and Bioelectronics, 2021, 183, 113233.

8. Yihui Jiang, Chunlan Wang, Nana Ma, Jie Chen, Chuanfei Liu, Fang Wang, Jiakun Xu^*, Zhiqi Cong^*, Regioselective aromatic O-demethylation with an artificial P450BM3 peroxygenase system, Catalysis Science &Technology, 2020, 10, 1219-1223.

9. Jiakun Xu, Chunlan Wang, Zhiqi Cong^*, Strategies for substrate-regulated p450 catalysis: from substrate engineering to co-catalysis, Chemistry–A European Journal, 2019, 25, 6853-6863.